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For the 2025-26 school year, there are 16 public schools serving 14,988 students in Mount Pleasant, SC (there are , serving 2,691 private students). 85% of all K-12 students in Mount Pleasant, SC are educated in public schools (compared to the SC state average of 92%). Mount Pleasant has one of the highest concentrations of top ranked public schools in South Carolina.

The top ranked public schools in Mount Pleasant, SC are Oceanside Collegiate Academy, Wando High School and Lucy Garrett Beckham High School. Overall testing rank is based on a school's combined math and reading proficiency test score ranking.

Mount Pleasant, SC public schools have an average math proficiency score of 76% (versus the South Carolina public school average of 43%), and reading proficiency score of 80% (versus the 52% statewide average). Schools in Mount Pleasant have an average ranking of 10/10, which is in the top 5% of South Carolina public schools.

Minority enrollment is 18% of the student body (majority Black), which is less than the South Carolina public school average of 53% (majority Black).